A practical high-rise reinforced concrete frame-shear-wall structure using nonlinear viscous dampers was modeled by some newly-developed numerical analysis tools. Then seismic responses of both the uncontrolled structure and the controlled structure using nonlinear viscous fluid dampers under major earthquakes were analyzed by nonlinear time-history analysis method based on the established numerical structural models. The structural responses of storey drift, base shear and structural damage distribution and development were obtained due to the excellent calculation ability of the numerical models and post-processing function of finite element analysis software. These analysis results of both the uncontrolled structure and the controlled structure were compared. And it shows that the seismic responses can be reduced and the seismic performance can be improved obviously in the controlled structure as nonlinear viscous dampers can effectively dissipate the input energy by earthquake.