Abstract: By virtue of a code for solving aeroelastic problems developed by the authors based on loosely coupled method, vortex-induced vibration of an elliptical cylinder at high Reynolds number is simulated. The ratio of major to minor axis for the elliptical cylinder approaches to 2, and the incident flow is perpendicular to major axis. Numerical results show that the lateral vibration dominates the vibration of the cylinder although the streamwise and lateral dynamic parameters are different. The vortex-induced vibration of the cylinder with two degree-of -freedoms exists streamwise and lateral lock-in phenomena, and with the increasing of the reduced velocity, the vortex shedding mode switches from out-of-phase 2S to in-phase 2S, which are the same as those for circular and square cylinders.