Statistical energy analysis (SEA) is adopted to analyze the coupling response of sound cavity-structure model at high frequency bands. The launch vehicle is designed to add isolators and active payload adapter to isolate the axial/lateral vibration. The finite element modeling and AutoSEA simulation are combined for this analysis. It is demonstrated that there is obvious decrease of vibration response for each frequency as well as the peak value of sound pressure. The significance of statistical energy analysis on high frequency model is fully illustrated by the final result.