In order to study the nonlinear interaction between CWR(continuously welded rail) and continuous beam carrying high-speed railway under traveling wave effect, the beam element with rigid elements was used to simulate the beam, the nonlinear bar element was used to simulate the longitudinal interaction between beam and tracks. The track-structure interaction model was established for the first time with considering the longitudinal and vertical seismic traveling wave effect. Taking a (60 +100 +60) m continuous beam on the Shanghai-Kunming line as a case, it was analyzed that the track made an impact on the seismic response of the beam and pier, the force characteristics of the track and pier was studied under the longitudinal and vertical traveling wave effect. Studies have shown that the track can improve the system natural frequency and reduce the seismic response of the continuous beam; the maximum longitudinal stress on the track under the traveling wave effect is up to 1.2 times under the uniform excitation; calculating the track stress, the impact of the vertical traveling wave effect on the track should be also considered.