Based on the principles of cylindrical helical spring compressive deformation, dynamic equations of metal rubber vibration isolation system were derived. The metal rubber dynamic stiffness, frequency response and vibration characteristic were analyzed under the condition of a simple harmonic excitation. According to the method of harmonic balance, the influence of excitation frequency on metal rubber displacement amplitude, and the influences of metal rubber displacement amplitude and excitation frequency on metal rubber dynamic stiffness were analyzed. On the basis of the analysis of metal rubber vibration isolation system, the influences of metal rubber height, working face cross-sectional area and displacement compression on shock isolation coefficient were studied. Shock isolation coefficient could provide a reference on the design of metal rubber and its applications in engineering.