Due to the fact that the existing isolation theories and technologies have many defects to isolate multi-dimensional vibrations, they are unable to meet the needs of the isolation in practice engineering, in which the excitation and the environment maybe change frequently. A novel metamorphic parallel mechanism is presented as the main body of the multi-dimensional vibration isolation system, in which some springs and dampers are installed on the active joints. The presented mechanism has two configurations, or can change to 3-CRR mechanism or CRU-2CRR parallel one, just by adjusting the configurations of the rT joint. The kinematics and dynamics equations of the presented isolation system are deduced, and then the modes, dynamics characteristics and vibration isolation of the isolation platform are studied. The simulations show that the system has good vibration effect in both two configurations, and it can isolate two sets of multi-dimensional vibrations.