This thesis analyzed interaction pattern of internal blast load in structure in detail, beginning with reflection on barrier of explosion block wave. Formula of shock wave pressure on side wall and top shell of structure with sphere shell is provided. Formula of axial and radial vibration on side wall of structure with classical elastic theory is derivated, and displacement-inner force curve of side wall, simulating structure material as anisotropic is calculated. Calculation results indicate that, axial displacement at upside of side wall is maximum, radial displacement and ring force at middle of side wall are maximum, and moment shear normal force under side wall are maximum.