This paper presents a crashworthiness design of the hexagonal thin-walled columns stiffened at two corners with circular tubes and dealt with triggers in the body. To formulate the complex crashworthiness design problem, radial basis function (RBF) has been utilized as the metamodels. In the optimization process, the specific energy absorption(Es) is set as the design object and maximum crushing force(Pm) is set as the design constraint. By ABAQUS’s FEM simulation and through nonlinear optimization, the ideal section profile parameters of different methodologies are compared and analyzed.An optimal section profile is finally found with high specific energy absorption (Es) of the structure. Parametric studies are also performed to investigate the influences of the design variables on the crash performance of this designed structure.