In order to achieve the optimized seismic performance design of frame exterior joints, a L9 (34) orthogonal table was established based on the orthogonal test principle and 9 groups of quasi-static tests were conducted.The main research factors were A (concrete strength), B (anchorage method) and C (longitudinal reinforcement ratio).Each factor was designed in three levels, namely A1 (C50), A2 (C60) and A3 (C70 ); B1 (bending), B2 (bolt) and B3 (paste welding); C1 (1.63%), C2 (2.08%) and C3 (2.58%).The test results were processed by the variance and range analysis, and then multiple comparisons were performed by the new multiple range method (SSR method).The results show that all of the three factors have significant effects on the ductility, energy consumption and ultimate bearing capacity of specimens.The ranking of the seismic performance influencing factors and their optimal combination are as follows: the order of influence on ductility is C>A>B, and the optimal combination for ductility is A3+B3+C1; the order of influence on energy dissipation capacity is A>C>B, and the optimal combination for energy dissipation capacity is A3+B3+C2; the order of influence on ultimate bearing capacity is C>A>B, and the optimal combination for energy dissipation capacity is A3+B1+C3.The preferred combination for comprehensive seismic performance is A3+B3+C1 or C2.The calculation results of the decrease rate of the average value of each factor were used as the basis for the analysis of the sensitivity of design combinations to each factor.The results show that each seismic performance index has different sensitivity to the factors of different exterior joints design combinations, and modifications could be performed aiming at the most sensitive factors.The research results have certain reference value and guiding significance for practical engineering.