An equivalent beam model considering the boundary of the isolation layer was established for base-isolated high-rising shear wall structures with large height-width ratio.The mode decomposition response spectrum method and the finite element nonlinear time history analysis method were developed.The comparative analysis of dynamic response under earthquake with the above two analysis methods, taking the scaled model of an actual structural with the ratio of height to width of 3.96 as an example, was conducted.The results obtained were compared with 3D FEM analysis.The following conclusions have been obtained: High calculation accuracy can be obtained in seismic response analysis of base-isolated high-rising shear wall structure with large height-width ratio using the equivalent beam model.The equivalent beam model parameter EIeq, considering the influence of the bending shear deformation, can be determined by the static calculation under the action of the lateral force distributed uniformly along the height of the structure.The equivalent beam model can be applied to the study of the universal law of high-rise seismic isolation structures.The example structure with a height-width ratio of 3.96 shows good anti-overturning performance under the action of 8-degree rare earthquake.The structure vibrates in the way of overall translation and slight flip and swing, and the horizontal lateral movement is mainly concentrated in the isolation layer.The rubber bearings are still under pressure, and the hysteretic curves of the isolation layer are full, and energy dissipation is significant.The method and the conclusion of correlation analysis can provide valuable reference for the further theoretical research and practical engineering application of high-rise shear wall base-isolated structures with large height-width ratio in high intensity areas.