Multi-ribbed slab structure (MRSS) is a new type of composite structure with specific characteristics which is composed of prefabricated multi-ribbed composite wall slab, cast-in-place floor slab and cast-in-suit concealed outer frame. In this paper, according to the basic components and construct characteristic of MRSS, the ultra low yield strength steel panels are used in the multi-ribbed composite wall slab, seismic response control of the multi-ribbed slab structures using the ultra low yield strength steel was explored. The nonlinear dynamic time-history analysis of the MRSS seismic control systems under horizontal earthquakes waves were carried out. The earthquake responses and energy dissipation mechanisms of the control structures were investigated. The effects of vibration reduction of the ultra low yield strength steel panel were discussed. The computing results show that the ultra low yield strength steel panel has obvious seismic mitigation effects, which a simple and effective seismic energy dissipation measures is provided for the multi-ribbed slab structure.